Derek A. Pratt

This study identifies vitamin B2 metabolism as a regulator of FSP1 stability, which prevents ferroptosis by maintaining FSP1 function through FAD cofactor binding.

This study identifies glycosaminoglycan-mediated lipoprotein uptake as a mechanism by which cancer cells resist ferroptosis and lipid oxidative stress.

The paper identifies ferroptosis regulators using a compendium of kinetic cell death modulatory profiles from 1,833 small molecules.