Author

Nisrine Sagar

Centre National de la Recherche ScientifiqueORCID 0000-0002-7352-3377Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexis‐Pierre BemelmansiD· 1 shared Anne‐Sophie HérardiD· 1 shared Cameron HéryiD· 1 shared Carole EscartiniD· 1 shared Céline Derbois· 1 shared Emmanuel BrouilletiD· 1 shared Éric BonnetiD· 1 shared Fanny PetitiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alexis‐Pierre BemelmansORCID

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2 papers

Recent·Most cited

Long-term memory formation depends on an astrocyte-to-neuron H2O2 signaling

Yasmine Rabah, Nisrine Sagar, Laure Pasquer, Pierre-Yves Plaçais, Thomas Préat

This study identifies an astrocyte-to-neuron H2O2 signaling pathway critical for long-term memory formation in Drosophila, with implications for Alzheimer's disease.

bioRxiv · Jul 11, 2023 · PreprintNeuroscience

Reactive astrocytes promote proteostasis in Huntington disease through the JAK2-STAT3 pathway

Laurene Abjean, Lucile Ben Haim, Miriam Riquelme‐Perez, Pauline Gipchtein, Céline Derbois, Marie-Ange Palomares, Fanny Petit, Anne‐Sophie Hérard, Marie‐Claude Gaillard, Martine Guillermier, Mylène Gaudin, Gwennaëlle Aurégan, Nisrine Sagar, Cameron Héry, Noëlle Dufour, , Carole Escartin

This study shows that activating the JAK2-STAT3 pathway in astrocytes reduces mutant Huntingtin aggregates and improves disease outcomes in Huntington's disease models.

Brain · Feb 17, 2022Peer-reviewedNeuroscience