Bärbel Stecher

This study identifies a bacterial protease that influences phage susceptibility and links it to host epithelial responses in ulcerative colitis.

The paper shows that E. faecalis evolves to metabolize fructoselysine, reducing S. Typhimurium colonization by limiting a key nutrient.

This study measures the fitness effects of 136 antimicrobial resistance genes in changing environments and finds that oxygen availability modulates their cost.

This paper develops conjugative plasmids that block antibiotic resistance plasmid spread by combining metabolic enhancement and plasmid spread mechanisms in microbial communities.

This study shows fumarate-based drugs modify gut bacteria via cysteine succination, affecting their functions and interactions in both isolated cultures and microbial communities.

This study shows colibactin-producing E. coli promote GEAC carcinogenesis by increasing proliferation, DNA damage, and cancer pathways, while also inducing autophagy and differentiation.

The paper investigates how microbial communities adapt metabolically in different environments, showing changes in carbon usage, biosynthesis, and interactions across monocultures, in vitro communities, and the mouse gut.

This study shows that sulfoquinovose is not metabolized by mice or humans but is degraded by gut microbiota, with differences in degradation pathways between mice and humans.