Author

Kevin Zhangxu

Amherst CollegeORCID 0000-0002-7477-6691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A G MurrayiD· 1 shared Aleigha R. LawlessiD· 1 shared Alfredo Quijano‐RubioiD· 1 shared Alyssa B. HuynhiD· 1 shared Asheema Khanna· 1 shared Ben EdwardsiD· 1 shared Birkley S. LimiD· 1 shared Chan Johng KimiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A G MurrayORCID

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2 papers

Recent·Most cited

Atypical PI3Ks coordinate chemotaxis, signaling dynamics, and multicellular development in Dictyostelium

Laith Bahlouli, Erik J. Zhang, Eric Jung, Taylor Brentjens, Elizabeth A. Rose, Harrison M. Drebin, Ben Edwards, Isabella Wischik, Alyssa B. Huynh, William Callahan, Jacqueline Shen, Susanna Li, Kevin Zhangxu, Marc Edwards

This paper identifies three atypical PI3Ks in Dictyostelium that regulate distinct aspects of chemotaxis, signaling, and multicellular development.

Journal of Cell Science · Aug 27, 2026Peer-reviewedCell Biology

Potent antitumor activity of a designed interleukin-21 mimic

Jung-Ho Chun, Birkley S. Lim, Suyasha Roy, Michael J. Walsh, Gita C. Abhiraman, Kevin Zhangxu, Tavus Atajanova, Or‐Yam Revach, Elisa C. Clark, Peng Li, Claire A. Palin, Asheema Khanna, Samantha J Tower, Rakeeb Kureshi, Megan T. Hoffman, , David A. Baker

This paper describes a designed IL-21 mimic, 21h10, which shows potent antitumor activity in multiple models and reduces toxicity through TNF blockade.

Science Immunology · Sep 26, 2025Peer-reviewedBiochemistry