Author

Asheema Khanna

Seattle Children's Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Surojit SarkariD· 3 shared Vandana KaliaiD· 3 shared A G MurrayiD· 1 shared Aleigha R. LawlessiD· 1 shared Alfredo Quijano‐RubioiD· 1 shared Anita Chaudhary· 1 shared Ashmitha RajendraniD· 1 shared Birkley S. LimiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersMolecular Biology

Surojit SarkarORCID

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Author profile →

3 papers

Recent·Most cited

SARS-CoV-2 S1 spike protein induces a temporal systemic immune response and promotes long-term anxiety-like behaviors

Leyre Merino-Galán, John Hemenway, Hawa Jagana, Taylor S. Jackson, Ashmitha Rajendran, Asheema Khanna, Sergio Ortiz‐Espinosa, Surojit Sarkar, Vandana Kalia, Siobhan S. Pattwell

This study investigates how SARS-CoV-2 S1 protein induces systemic immune responses and long-term anxiety-like behaviors in mice.

bioRxiv · Jun 18, 2026 · PreprintMolecular Biology

Divergent effects of a Treg selective IL-2 mutein on Influenza-specific T cell responses

Joseph R. Albe, Anita Chaudhary, Asheema Khanna, Kristin N. Weinstein, Steven F. Ziegler, Vandana Kalia, Surojit Sarkar, Daniel Campbell

This study examines how a Treg-selective IL-2 mutein affects influenza-specific T cell responses, showing opposing effects based on administration timing.

The Journal of Immunology · Dec 10, 2025Peer-reviewedImmunology

Potent antitumor activity of a designed interleukin-21 mimic

Jung-Ho Chun, Birkley S. Lim, Suyasha Roy, Michael J. Walsh, Gita C. Abhiraman, Kevin Zhangxu, Tavus Atajanova, Or‐Yam Revach, Elisa C. Clark, Peng Li, Claire A. Palin, Asheema Khanna, Samantha J Tower, Rakeeb Kureshi, Megan T. Hoffman, , David A. Baker

This paper describes a designed IL-21 mimic, 21h10, which shows potent antitumor activity in multiple models and reduces toxicity through TNF blockade.

Science Immunology · Sep 26, 2025Peer-reviewedBiochemistry