Author

Johan Vande Voorde

Cancer Research UK Scotland InstituteORCID 0000-0002-7686-0926Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

David P. SumptoniD· 3 shared Alejandro Huerta UribeiD· 2 shared Alexander CollingsiD· 1 shared Alexander MuiriD· 1 shared Alexandra L. Howell· 1 shared Amanda J. McFarlane· 1 shared Anand ManoharaniD· 1 shared Andrew E. HoganiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

David P. SumptonORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 17, 2025

Thiol Scarcity in Cerebrospinal Fluid Renders Leptomeningeal Acute Lymphoblastic Leukaemia Therapeutically Vulnerable to Ferroptosis

Nikolai Gajic, Rhona Christie, Shirley Lam…·Christina Halsey

This paper identifies a metabolic vulnerability in leptomeningeal ALL cells due to thiol scarcity in CSF, making them susceptible to ferroptosis through disruption of selenocysteine biosynthesis and GPX4 activity.

DOI 10.64898/2025.12.15.693383

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyEMBO ReportsPeer-reviewedJul 23, 2025

Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung

Declan Whyte, Sophie L Fisher, Christopher G J McKenzie…·Cassie J. Clarke

15 citationstop 3%

mouseexperimental assay

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ImmunologybioRxivPreprintMar 19, 2025

ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity

Benjamin Jenkins, Yasmin R Jenkins, Fernando M. Ponce-Garcia…·Nicholas Jones

This paper shows that inhibiting ABHD11 reduces T cell cytokine production and alleviates autoimmunity by altering sterol metabolism and LXR activation.

DOI 10.1101/2025.03.19.643996

humanmouse

𝕏 PostBluesky