Author

Tao Yang

Stanford MedicineORCID 0000-0002-7698-3440Unclaimed ORCID profile · follow to get notified of new preprints

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Tao Yang10 papers · BGI Research

Biology Disciplines

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Neuroscience· 4

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Organism:mouse· 4 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Frank M. LongoiD· 4 shared Amira Latif‐HernandeziD· 2 shared Katrin I. AndreassoniD· 2 shared Paras Singh MinhasiD· 2 shared Aarooran Sivakumaran DurairajiD· 1 shared Austin KangiD· 1 shared Brenita C. JenkinsiD· 1 shared Christopher A. Chapleau· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersNeuroscience

Frank M. LongoORCID

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4 papers

Recent·Most cited

Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies

Paras Singh Minhas, Jeffrey R. Jones, Amira Latif‐Hernandez, Yuki Sugiura, Aarooran Sivakumaran Durairaj, Qian Wang, Siddhita D. Mhatre, Takeshi Uenaka, Joshua D. Crapser, Travis E. Conley, Hannah E. Ennerfelt, Yoo Jin Jung, Ling Liu, Praveena Prasad, Brenita C. Jenkins, , Katrin I. Andreasson

This study shows that inhibiting IDO1 restores hippocampal glucose metabolism and rescues cognition in Alzheimer's disease models.

Science · Aug 22, 2024Peer-reviewedNeuroscience

A small-molecule TrkB ligand improves dendritic spine phenotypes and atypical behaviors in female Rett syndrome mice

Destynie Medeiros, Karen Ayala-Baylon, Hailey X. Egido‐Betancourt, Eric C. Miller, Christopher A. Chapleau, Holly Robinson, Mary L. Phillips, Tao Yang, Frank M. Longo, Wei Li, Lucas D. Pozzo‐Miller

This study shows that the small-molecule TrkB agonist LM22A-4 improves dendritic spine morphology and reduces aggressive behaviors in female Rett syndrome mice.

Disease Models & Mechanisms · May 24, 2024Peer-reviewedNeuroscience

A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model

Amira Latif‐Hernandez, Tao Yang, Robert R. Butler, Patricia Morán Losada, Paras Singh Minhas, Halle White, Kevin C Tran, Harry Liu, Danielle A. Simmons, Vanessa F. Langness, Katrin I. Andreasson, Tony Wyss‐Coray, Frank M. Longo

BD10-2, a TrkB/C partial agonist, improves memory and LTP deficits in Alzheimer's mice by modulating synaptic signaling and microglial transcriptomic changes.

Alzheimer s & Dementia · May 23, 2024Peer-reviewedNeuroscience

Post-stroke administration of the p75 neurotrophin receptor modulator, LM11A-31, attenuates chronic changes in brain metabolism, increases neurotransmitter levels, and improves recovery

Thuy‐Vi V. Nguyen, Rachel H. Crumpacker, Kylie Calderon, Frankie G. Garcia, Jacob C. Zbesko, Jennifer Beischel Frye, Selena Gonzalez, Danielle A. Becktel, Tao Yang, Marco A. Tavera-Garcia, Helena Willington Morrison, Rick G. Schnellmann, Frank M. Longo, Kristian P. Doyle

This study shows that LM11A-31, a p75NTR modulator, improves stroke recovery by enhancing brain metabolism, neurotransmitter levels, and reducing neurodegeneration in mice.

Journal of Pharmacology and Experimental Therapeutics · Dec 10, 2021Peer-reviewedNeuroscience