Author

Lea Sirignano

Heidelberg UniversityORCID 0000-0002-7989-5833Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Caroline Laura ReltoniD· 2 shared Darina CzamaraiD· 2 shared Fabian StreitiD· 2 shared Henning W. TiemeieriD· 2 shared Janine F. FelixiD· 2 shared Jari M. T. LahtiiD· 2 shared Jordi SunyeriD· 2 shared Josef FrankiD· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Caroline Laura ReltonORCID

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2 papers

Recent·Most cited

Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills.

Doretta Caramaschi, Alexander Neumann, Andrés Cárdenas, Gwen N. Tindula, Silvia Alemany, Lea Zillich, Giancarlo Pesce, Jari M. T. Lahti, Alexandra Havdahl, Rosa H. Mulder, Janine F. Felix, Henning W. Tiemeier, Lea Sirignano, Josef Frank, Stephanie H. Witt, , Gemma C. Sharp

This study examines DNA methylation at birth and its association with childhood cognitive skills, finding weak single CpG site associations and one region near DUSP22 linked to non-verbal cognition.

Molecular Psychiatry · Feb 10, 2022Peer-reviewedDevelopmental Biology

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

Jenny van Dongen, Fiona A. Hagenbeek, Matthew J Suderman, Peter J. Roetman, Karen Sugden, Andreas G. Chiocchetti, Khadeeja Ismail, Rosa H. Mulder, Jonathan D. Hafferty, Mark J. Adams, Rosie May Walker, Stewart W. Morris, Jari M. T. Lahti, Leanne K. Küpers, Geòrgia Escaramís, , Dorret Irene Boomsma

This paper identifies DNA methylation sites associated with aggression through a meta-analysis of epigenome-wide studies across different age groups and tissues.

bioRxiv · Jul 22, 2020 · PreprintGenetics