Author

Santosh Pothula

Yale UniversityORCID 0000-0002-8019-3396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:electronic health records· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alex C. KwaniD· 2 shared Christopher PittengeriD· 2 shared Danielle M. GerhardiD· 2 shared Farhan AliiD· 2 shared Katherine Sweasy· 2 shared Ronald S. DumaniD· 2 shared Anil AnnamneediiD· 1 shared Anna BethiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Alex C. KwanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bassoon is required for adult ocular dominance plasticity and experience-induced changes in synapsin phosphorylation in visual cortex

Cornelia Schöne, Carolina Montenegro‐Venegas, Debarpan Guhathakurta, Bianka Barthel, Franziska Greifzu, Josephin Boehner, Santosh Pothula, Eneko Pina-Fernández, Anna Beth, Anil Annamneedi, Martin Heine, Eckart Dieter Gundelfinger, Siegrid Löwel, Anna Fejtová

This study shows that bassoon is essential for adult ocular dominance plasticity but not juvenile plasticity, involving presynaptic changes in synapsin phosphorylation.

bioRxiv · Sep 27, 2026 · PreprintNeuroscience

Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation

Farhan Ali, Ling-Xiao Shao, Danielle M. Gerhard, Katherine Sweasy, Santosh Pothula, Christopher Pittenger, Ronald S. Duman, Alex C. Kwan

This study shows that a Shank3 mutation causes elevated calcium in dendritic spines due to reduced inhibition from SST interneurons, and correcting this improves learning deficits.

Molecular Psychiatry · Mar 11, 2020Peer-reviewedNeuroscience

Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines

Farhan Ali, Danielle M. Gerhard, Katherine Sweasy, Santosh Pothula, Christopher Pittenger, Ronald S. Duman, Alex C. Kwan

This study shows that ketamine suppresses SST interneurons, leading to increased calcium signals in dendritic spines of pyramidal neurons in the medial prefrontal cortex of awake mice.

Nature Communications · Jan 7, 2020Peer-reviewedNeuroscience