Yuk Fai Leung

Piezo3 is a novel mechanosensitive Piezo ion channel in vertebrates

The paper identifies Piezo3 as a new PIEZO paralog in vertebrates, shows its mechanosensitive function in HEK293T cells, and demonstrates its role in zebrafish mechanosensation and light response.

Zebrafish Functional Screening of FDA-Approved Drugs for Autosomal Dominant Retinitis Pigmentosa Caused by RHODOPSIN Q344X Mutation

This study screens FDA-approved drugs in a zebrafish model of autosomal dominant retinitis pigmentosa, identifying four compounds that improve visual behavior by distinct mechanisms.

Tensor analysis of animal behavior by matricization and feature selection

This study evaluates matricization and feature selection methods for analyzing multi-dimensional tensor behavioral data from zebrafish, showing improved classification performance and revealing new behavioral differences.

Drug Screening with Zebrafish Visual Behavior Identifies Carvedilol as a Potential Treatment for Retinitis Pigmentosa

This study screens drugs using zebrafish visual behavior to identify carvedilol as a potential treatment for retinitis pigmentosa.