Qionghua Zhu

The paper integrates mRNA and protein isoform data in human RPE-1 cells to reveal widespread translation of alternative transcripts and proteolytic processing as a major source of proteome complexity.

This study investigates how the order of early mutations affects tumor initiation in colorectal cancer using engineered murine organoids, finding that mutation order influences tumorigenic properties and immune interactions.

PB-scope uses deep learning to analyze PB dynamics and identifies drugs affecting JAK signaling pathway.

CASB is a sample barcoding method for single-cell sequencing that enables accurate multiplexing across different sequencing techniques and detects doublets with high sensitivity.

CIGAR-seq identifies mRNA modification regulators through CRISPR screening and RNA modification readout, revealing NSUN6 as a novel m5C methyltransferase.