Author

Patricia Rothe

Max Planck SocietyORCID 0000-0002-8066-7993Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alessa R. RingeliD· 1 shared Alexander MeissneriD· 1 shared Alexandra L. MatteiiD· 1 shared Andrea EspositoiD· 1 shared Andrea M. ChiarielloiD· 1 shared Angelika GründlingiD· 1 shared Cesar A. Prada‐MedinaiD· 1 shared Christina PaliouiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Alessa R. RingelORCID

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2 papers

Recent·Most cited

Cytosolic factors controlling PASTA kinase-dependent ReoM phosphorylation

Patricia Rothe, Sabrina Wamp, Lisa Rosemeyer, Jeanine Rismondo, Joerg Doellinger, Angelika Gründling, Sven Halbedel

This study identifies GpsB as an activator of PrkA, a PASTA kinase, and shows that ReoM phosphorylation is regulated by growth phase and phosphatase PrpC, with MurA's conformation and interaction with ReoM playing a key role.

Molecular Microbiology · Sep 8, 2024Peer-reviewedMicrobiology

Promoter repression and 3D-restructuring resolves divergent developmental gene expression in TADs

Alessa R. Ringel, Quentin Szabo, Andrea M. Chiariello, Konrad Chudzik, Robert Schöpflin, Patricia Rothe, Alexandra L. Mattei, Tobias Zehnder, Dermot Harnett, Verena Laupert, Simona Bianco, Sara Hetzel, Mai H.Q. Phan, Magdalena Schindler, Daniel M. Ibrahim, , Michael I. Robson

The paper shows that divergent gene expression within TADs is resolved through TAD restructuring and DNA methylation, not enhancer-promoter compatibility or position.

bioRxiv · Oct 8, 2021 · PreprintGenetics