Author

Mai H.Q. Phan

Max Planck Institute for Molecular Genetics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Genetics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:gene regulatory network inference· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3

Frequent Co-Authors

Daniel M. IbrahimiD· 3 shared Blanka MajchrzyckaiD· 2 shared Cesar A. Prada‐MedinaiD· 2 shared Christina PaliouiD· 2 shared Lars WittleriD· 2 shared Martin VingroniD· 2 shared Robert Schöpflin· 2 shared Stefan MundlosiD· 2 shared

Activity by Year

2019-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Daniel M. IbrahimORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Osmotic niche changes as multifaceted trigger of cellular regenerative processes in organ injury

Matthias R. Kollert, Taimoor H. Qazi, Mai H.Q. Phan, Blanka Majchrzycka, Andreas F. Thünemann, Daniel M. Ibrahim, Viola Vogel B, David J. Mooney, Georg N. Duda

This study shows that osmolality changes in bone marrow after fracture enhance mesenchymal stromal cell regeneration by altering ECM viscoelasticity and chromatin structure.

bioRxiv · Sep 7, 2025 · PreprintBioengineering

Enhancer adoption by an LTR retrotransposongenerates viral-like particles causingdevelopmental limb phenotypes

Juliane Glaser, Giulia Cova, Beatrix Fauler, Cesar A. Prada‐Medina, Virginie Stanislas, Mai H.Q. Phan, Robert Schöpflin, Yasmin Aktas, Martin Franke, Guillaume Andrey, Natalia Bartzoka, Christina Paliou, Verena Laupert, Wing-Lee Chan, Lars Wittler, , Stefan Mundlos

The paper shows that activation of an LTR retrotransposon in the embryo leads to viral-like particle production, causing limb malformations through apoptotic cell death.

Nature Genetics · Jul 1, 2025Peer-reviewedDevelopmental Biology

Conservation of Regulatory Elements with Highly Diverged Sequences Across Large Evolutionary Distances

Mai H.Q. Phan, Tobias Zehnder, Fiona Puntieri, Andreas Magg, Blanka Majchrzycka, Milan Antonović, Hannah M. Wieler, Bai-Wei Lo, Damir Baranas̆ić, Boris Lenhard, Ferenc Müller, Martin Vingron, Daniel M. Ibrahim

The paper identifies functionally conserved regulatory elements across distantly related vertebrates despite sequence divergence using a synteny-based method.

Nature Genetics · May 27, 2025Peer-reviewedGenetics

Promoter repression and 3D-restructuring resolves divergent developmental gene expression in TADs

Alessa R. Ringel, Quentin Szabo, Andrea M. Chiariello, Konrad Chudzik, Robert Schöpflin, Patricia Rothe, Alexandra L. Mattei, Tobias Zehnder, Dermot Harnett, Verena Laupert, Simona Bianco, Sara Hetzel, Mai H.Q. Phan, Magdalena Schindler, Daniel M. Ibrahim, , Michael I. Robson

The paper shows that divergent gene expression within TADs is resolved through TAD restructuring and DNA methylation, not enhancer-promoter compatibility or position.

bioRxiv · Oct 8, 2021 · PreprintGenetics

Wnt11/Fzd7 signaling compartmentalizes AKAP2/PKA to regulate L-type Ca2+ channel

Kitti Csályi, Tareck Rharass, Maike Schulz, Mai H.Q. Phan, Paulina Wakula, Ketaki N. Mhatre, David O. Plotnick, Andreas A. Werdich, Henrik Zauber, Matthias D. Sury, Matthias Selbach, Frank R. Heinzel, Enno Klußmann, Daniela Panáková

The paper shows Wnt11/Fzd7 signaling regulates L-type Ca2+ channels by compartmentalizing AKAP2/PKA, essential for heart development in zebrafish.

bioRxiv · Aug 20, 2019 · PreprintDevelopmental Biology