Author

Quentin Szabo

Centre National de la Recherche ScientifiqueORCID 0000-0002-3539-7875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Frédéric BantigniesiD· 2 shared Giacomo CavalliiD· 2 shared Alessa R. RingeliD· 1 shared Alexander MeissneriD· 1 shared Alexandra L. MatteiiD· 1 shared Andrea EspositoiD· 1 shared Andrea M. ChiarielloiD· 1 shared Andreas E. MooriD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

Frédéric BantigniesORCID

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3 papers

Recent·Most cited

A Scaffolding Element Rewires Local 3D Chromatin Architecture During Differentiation

Ivana Jerković, Marco Di Stefano, Hadrien Reboul, Michael Szalay, Davide Normanno, Flora Paldi, Giorgio Lucio Papadopoulos, Quentin Szabo, Frédéric Bantignies, Giacomo Cavalli

This study identifies a scaffolding element that drives chromatin rewiring during differentiation by modulating 3D structure and transcription.

Nature Communications · Sep 15, 2026Peer-reviewedCell Biology

RoCK and ROI: Single-cell transcriptomics with multiplexed enrichment of selected transcripts and region-specific sequencing

Giulia Moro, Izaskun Mallona, Malwine Barz, Joël Maillard, Michael David Brügger, Hassan Fazilaty, Quentin Szabo, Tomáš Valenta, Kristina Handler, Fiona Kerlin, Lorenz Bastian, Claudia Dorothea Baldus, Andreas E. Moor, Robert P. Zinzen, Mark D. Robinson, , Konrad Basler

RoCK and ROI improves single-cell transcriptomics by targeting specific transcripts and regions, enhancing detection of critical biological features.

Nature Communications · Dec 10, 2025Peer-reviewedGenomics

Promoter repression and 3D-restructuring resolves divergent developmental gene expression in TADs

Alessa R. Ringel, Quentin Szabo, Andrea M. Chiariello, Konrad Chudzik, Robert Schöpflin, Patricia Rothe, Alexandra L. Mattei, Tobias Zehnder, Dermot Harnett, Verena Laupert, Simona Bianco, Sara Hetzel, Mai H.Q. Phan, Magdalena Schindler, Daniel M. Ibrahim, , Michael I. Robson

The paper shows that divergent gene expression within TADs is resolved through TAD restructuring and DNA methylation, not enhancer-promoter compatibility or position.

bioRxiv · Oct 8, 2021 · PreprintGenetics