Author

Xiao Yin Lee

KU LeuvenORCID 0000-0002-8077-6030Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Abhimanyu Kumar SinghiD· 1 shared Annelies StevaertiD· 1 shared Arnout R. D. VoetiD· 1 shared Benjamin Van LoyiD· 1 shared Bert VanmecheleniD· 1 shared Besir KrasniqiiD· 1 shared Brent De WijngaertiD· 1 shared Cato MestdaghiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Abhimanyu Kumar SinghORCID

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1 paper

Recent·Most cited

A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses

Benjamin Van Loy, Eugènia Pujol, Kenichi Kamata, Xiao Yin Lee, Nikolai Bakirtzoglou, Ria Van Berwaer, Julie Vandeput, Cato Mestdagh, Leentje Persoons, Brent De Wijngaert, Quinten Goovaerts, Sam Noppen, Maarten Jacquemyn, Kourosh Ahmadzadeh, Eline Bernaerts, , Annelies Stevaert

This paper identifies EPB-113, a guanidine-based inhibitor of coronavirus nsp15 endoribonuclease, which suppresses viral replication and selects for interferon-susceptible mutants.

PLoS Pathogens · Feb 11, 2025Peer-reviewedMicrobiology