Charley Xia

This paper evaluates methods to estimate lifetime brain atrophy from a single MRI scan and identifies genetic correlates, finding that the residual method best captures brain shrinkage and has strong heritability.

GSOR and MTAO detect widespread cis-regulatory effects on bovine complex traits by linking gene expression with genetic scores and multi-trait associations.

This study identifies 1,257 genetic variants associated with human personality traits using large-scale GWAS and finds widespread genetic correlations with behaviors and life outcomes.

This study uses Mendelian randomization to investigate the causal relationship between socioeconomic status and brain structure, finding that SES is protective against white matter hyperintensities independent of cognitive ability.

This study identifies genetic variants associated with income and shows they correlate with health outcomes and educational attainment.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

The paper constructs a cattle Genotype-Tissue Expression atlas and identifies genetic regulatory variants linked to gene expression and traits in cattle.

The paper examines genetic and shared couple environmental factors influencing smoking and alcohol use in the UK population using family and couple data.

The paper investigates the genetic and environmental contributions to stressful life events and their overlap with depression and neuroticism using a large family-based sample.

The paper uses family data to estimate genetic effects on intelligence and personality, finding that rare variants explain more variance than previously reported using unrelated individuals.

This study identifies shared genetic and couple-associated environmental factors contributing to both clinical and self-declared depression risks.