Pau Navarro

The paper introduces the RUMIGEN EpiChip, a DNA methylation array for cattle, demonstrating its utility in studying phenotypic variation and age prediction through methylation analysis.

The paper identifies 505 protein quantitative trait loci (pQTL) in a Scottish cohort, linking proteins to complex traits and diseases, and highlights potential drug targets.

GSOR and MTAO detect widespread cis-regulatory effects on bovine complex traits by linking gene expression with genetic scores and multi-trait associations.

The paper investigates epitope effects in pQTL studies, finding that only 12% or less of cis-pQTL results are influenced by missense-mediated epitope effects.

The paper describes a large DNA methylation dataset from the Generation Scotland cohort, providing methylation profiles and associated phenotypes for research purposes.

The paper evaluates regional heritability mapping methods to identify QTLs in Soay sheep, finding that some methods detect new trait-associated regions not found by GWAS.

The paper identifies genetic regulators of 184 neuro-related proteins in human plasma and links them to disease traits and drug targets.

The paper estimates cancer risk in Lynch syndrome carriers using UK Biobank data, finding elevated colorectal and endometrial cancer risks but not breast cancer.

The paper applies a method to estimate heritability in a wild sheep population, finding that including an identity-by-descent GRM improves model fit for polygenic traits but not monogenic ones.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

This study simulates Atlantic salmon breeding programs to show that mixing between parallel year groups improves genomic prediction accuracy by reducing genetic distance and increasing genetic variation.

The paper identifies parent-of-origin effects on the methylome linked to aging rates by analyzing CpG methylation in a large family cohort.

This study examines how SNP density affects heritability estimates and QTL detection in Soay sheep body size traits using two SNP datasets.

The paper constructs a cattle Genotype-Tissue Expression atlas and identifies genetic regulatory variants linked to gene expression and traits in cattle.

The paper identifies genetic loci regulating glycosylation of transferrin and IgG, finding both shared and protein-specific associations and proposing tissue-specific transcription factor regulation.

SNHap-RHM jointly maps common and rare genetic variation affecting complex traits by combining SNP and haplotype-based genomic relationship matrices, identifying significant genomic regions for height and MDD.

This study identifies modifiable parent-of-origin effects on DNA methylation by analyzing genetic and environmental factors in a large cohort.

This study uses genome-wide methylation data to assess the impact of smoking and gene-smoking interactions on obesity-related traits, showing improved variance explanation compared to traditional methods.

The paper investigates the genetic and environmental contributions to stressful life events and their overlap with depression and neuroticism using a large family-based sample.

The paper uses family data to estimate genetic effects on intelligence and personality, finding that rare variants explain more variance than previously reported using unrelated individuals.

This study identifies shared genetic and couple-associated environmental factors contributing to both clinical and self-declared depression risks.