Author
New York UniversityORCID 0000-0003-3532-7671Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Alem W. Kahsai, Natalia Pakharukova, Henry Y. Kwon…·Robert J. Lefkowitz
This study identifies small-molecule inhibitors of beta-arrestins and elucidates their mechanism, offering a framework for modulating GPCR signaling.
Hyunggu Hahn, Emmanuel Flores-Espinoza, Anthony H. Nguyen…·Alex Rojas Bie Thomsen
The paper identifies a conserved hydrophobic interaction that mediates competition between GPCR transducers and regulators.
Emmanuel Flores-Espinoza, Hyunggu Hahn, Alex Rojas Bie Thomsen
The vasopressin V2 receptor activates G proteins and β-arrestins at the lysosomal surface before being degraded.
Chloe J. Peach, Raquel Tonello, Elisa Damo…·Nigel W. Bunnett
This paper identifies NRP1 as a co-receptor for NGF and TrkA pain signaling and shows that targeting NRP1 or GIPC1 can reduce chronic pain without opioid use.