Author
New York UniversityORCID 0000-0003-1638-8911Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Alem W. Kahsai, Natalia Pakharukova, Henry Y. Kwon…·Robert J. Lefkowitz
This study identifies small-molecule inhibitors of beta-arrestins and elucidates their mechanism, offering a framework for modulating GPCR signaling.
Hyunggu Hahn, Emmanuel Flores-Espinoza, Anthony H. Nguyen…·Alex Rojas Bie Thomsen
The paper identifies a conserved hydrophobic interaction that mediates competition between GPCR transducers and regulators.
Emmanuel Flores-Espinoza, Hyunggu Hahn, Alex Rojas Bie Thomsen
The vasopressin V2 receptor activates G proteins and β-arrestins at the lysosomal surface before being degraded.
Carole A. Daly, Adam Wright, Raimond Heukers…·Bianca Plouffe
The paper shows that US28's Gq/11 signaling from the plasma membrane, not endosomes, primarily drives gene expression related to glioblastoma proliferation and inflammation.
Chloe J. Peach, Raquel Tonello, Elisa Damo…·Nigel W. Bunnett
This paper identifies NRP1 as a co-receptor for NGF and TrkA pain signaling and shows that targeting NRP1 or GIPC1 can reduce chronic pain without opioid use.