Florian Roisné-Hamelin

The paper shows that SMC hinge domains selectively allow ssDNA to bypass obstacles during DNA loop extrusion, revealing a conserved mechanism across SMC complexes.

This study determines the structure of a type II Wadjet SMC complex from Neobacillus vireti, revealing structural differences from type I systems and insights into prokaryotic SMC evolution.

The paper reveals that Rap1 inhibits Ku's NHEJ function at telomeres by obstructing Ku's inward translocation, preventing promiscuous repair.

This paper introduces a cloning method for rapidly generating expression constructs of multi-subunit protein complexes in various hosts.

The paper reveals how SMC JET nuclease recognizes and cleaves plasmid DNA by mechanically bending residual unextruded DNA, identifying key structural elements involved in the process.

The paper shows JetABCD SMC complexes restrict small circular plasmids by cleaving them, while linear plasmids are not restricted, and presents a structural model for this process.