Yan Li

This study identifies a bipartite mechanism for condensin II activation in mitosis, showing how M18BP1 relieves autoinhibition and enables DNA loop formation.

The paper presents structures of a Lamassu defence system from Salmonella enterica, revealing how LmuA nuclease effector is activated by oligomerization and DNA cleavage.

The paper reveals how SMC JET nuclease recognizes and cleaves plasmid DNA by mechanically bending residual unextruded DNA, identifying key structural elements involved in the process.

The paper shows JetABCD SMC complexes restrict small circular plasmids by cleaving them, while linear plasmids are not restricted, and presents a structural model for this process.

This paper introduces eHi-C, a protocol for 3D genome mapping using small cell populations, achieving high-quality results comparable to traditional Hi-C with fewer cells.