Author

Thomas M. Coffman

Duke-NUS Medical SchoolORCID 0000-0002-8433-1629Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:GWAS / association mapping· 2 Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adriana M. HungiD· 1 shared Benjamin F. VoightiD· 1 shared Benjamin L. FarahiD· 1 shared Chengxiang QiuiD· 1 shared Christopher D. BrowniD· 1 shared Enrico G. PetrettoiD· 1 shared Hongbo LiuiD· 1 shared Jacklyn N. HellwegeiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Adriana M. HungORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A Cross-Species Systems Genetics Framework Identifies Causal Genes in Diabetic Nephropathy

Kunal Mishra, Rashidah Binte Sakban, Sujithra Shankar, Jasmine Wong, Benjamin L. Farah, Jing Guo, Jianhong Ching, Ming Shen Tham, Jean‐Paul Kovalik, Susan B. Gurley, Enrico G. Petretto, Nicholas S. Tolwinski, Thomas M. Coffman, Jacques V. Behmoaras

This paper identifies causal genes in diabetic nephropathy using a cross-species systems genetics framework, finding 192 candidate genes with 40% validated in humans.

bioRxiv · Jul 1, 2026 · PreprintSystems Biology

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

Xin Sheng, Yuting Guan, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Steven Vitale, Zhen Miao, Matthew J. Seasock, Matthew Palmer, Myung K. Shin, Kevin L. Duffin, Steven S. Pullen, Todd L. Edwards, Jacklyn N. Hellwege, , Katalin Suszták

The paper maps genetic variants to cell types in the kidney to identify disease mechanisms and drug targets.

Nature Genetics · Aug 12, 2021Peer-reviewedGenetics