Author

João M.L. Dias

University of CambridgeORCID 0000-0002-8451-3537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan R. LehmanniD· 1 shared Andrea DegasperiiD· 1 shared Charlotta G. LebedenkoiD· 1 shared Cherif BadjaiD· 1 shared Ching Chiek KohiD· 1 shared Chris BakaliD· 1 shared Christian FrezzaiD· 1 shared Chryssostomos ChatgilialogluiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alan R. LehmannORCID

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2 papers

Recent·Most cited

Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling

Peiyuan Chai, Jonathan Perr, Lauren Kageler, Charlotta G. Lebedenko, João M.L. Dias, Eliza Yankova, Jeffrey D. Esko, Konstantinos Tzelepis, Ryan A. Flynn

The paper identifies heparan sulfate proteoglycans as key organizers of cell surface glycoRNA and RNA binding proteins, showing their role in regulating growth factor signaling.

bioRxiv · Jul 25, 2024 · PreprintMolecular Biology

A rare genetic disorder provides insights into mechanisms of early-onset neurodegeneration

Cherif Badja, Sophie Momen, Ching Chiek Koh, Soraya Boushaki, Theodoros I. Roumeliotis, Zuza Kozik, Ian Jones, Vicky Bousgouni, João M.L. Dias, Marios G. Krokidis, Jamie Young, Hongwei Chen, Ming Hui Yang, France Docquier, Yasin Memari, , Serena Nik‐Zainal

This study investigates neurodegeneration in Xeroderma pigmentosum using stem cell-derived neurons, identifying endoplasmic reticulum stress and UPS dysfunction as key factors and developing an early detection assay.

medRxiv · May 22, 2023 · PreprintGenetic & Genomic Medicine