Author

Jordi Romero‐Giménez

Biomedical Research Networking Center on Neurodegenerative DiseasesORCID 0000-0002-8459-9895Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:rat· 2 Organism:mouse· 1

Frequent Co-Authors

Ariadna LagunaiD· 3 shared Joan CompteiD· 3 shared Miquel VilaiD· 3 shared Alba NicolauiD· 2 shared Annabelle ParentiD· 2 shared Camille Guillard-SirieixiD· 2 shared Marina Lorente PicóniD· 2 shared Marta González-SepúlvedaiD· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Ariadna LagunaORCID

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3 papers

Recent·Most cited

Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related multisystem neurodegenerative deficits

Ariadna Laguna, Núria Peñuelas, Marta González-Sepúlveda, Alba Nicolau, Sébastien Arthaud, Camille Guillard-Sirieix, Marina Lorente Picón, Joan Compte, Lluís Miquel-Rio, Helena Xicoy, Jiong Liu, Annabelle Parent, Thais Cuadros, Jordi Romero‐Giménez, Gemma Pujol, , Miquel Vila

This paper creates a transgenic mouse model that mimics human neuromelanin accumulation in catecholaminergic neurons, leading to age-related neurodegenerative deficits.

Nature Communications · Oct 11, 2024Peer-reviewedNeuroscience

Non-ablative disease-modifying effects of magnetic resonance-guided focused ultrasound in neuromelanin-producing parkinsonian rodents

Joan Compte, Marion Tible, Thaïs Cuadros, Jordi Romero‐Giménez, Ariadna Laguna, Jean‐François Aubry, Erik Dumont, Charlotte Constans, Thomas Tiennot, Mathieu David Santin, Stéphane Lehéricy, Miquel Vila

Transcranial focused ultrasound reduces neuromelanin accumulation and provides therapeutic benefits in parkinsonian rats without additional interventions.

bioRxiv · Aug 8, 2023 · PreprintNeuroscience

In vivo reduction of age-dependent neuromelanin accumulation mitigates features of Parkinson's disease

Marta González-Sepúlveda, Joan Compte, Thaïs Cuadros, Alba Nicolau, Camille Guillard-Sirieix, Núria Peñuelas, Marina Lorente Picón, Annabelle Parent, Jordi Romero‐Giménez, Joana M. Cladera-Sastre, Ariadna Laguna, Miquel Vila

This study reduces age-related neuromelanin accumulation in a humanized rodent model, mitigating Parkinson's disease features by preserving dopamine homeostasis and neuronal integrity.

Brain · Nov 23, 2022Peer-reviewedNeuroscience