This study conducts a genome-wide association study to identify genetic variants linked to musical beat synchronization, finding high polygenicity with 69 significant loci and heritability estimates of 13%-16%.

Nature Human Behaviour · Jun 16, 2022Peer-reviewedGenetics

Genetic analyses identify widespread sex-differential participation bias

Nicola Pirastu, Mattia Cordioli, Priyanka Nandakumar, Gianmarco Mignogna, Abdel Abdellaoui, Benjamin Hollis, Masahiro Kanai, Veera Manikandan Rajagopal, Pietro Della Briotta Parolo, Nikolas A. Baya, Caitlin E. Carey, Juha M Karjalainen, Thomas D. Als, Matthijs D. van der Zee, Felix R. Day, , Andrea Ganna

The paper identifies sex-differential participation bias in genetic studies by performing GWAS on sex in 3.3 million individuals, finding 158 loci associated with sex and highlighting traits like BMI that may influence participation.

Nature Genetics · Apr 22, 2021Peer-reviewedGenetics

Genetic determinants of daytime napping and effects on cardiometabolic health

Hassan S. Dashti, Iyas Daghlas, Jacqueline M. Lane, Yunru Huang, Miriam S. Udler, Heming Wang, Hanna Maria Ollila, Samuel E. Jones, Jaegil Kim, Andrew R. Wood, Michelle Agee, Adam Auton, Robert K. Bell, Katarzyna Bryc, Sarah K. Clark, , Richa Saxena

This study identifies genetic loci associated with daytime napping and finds potential causal links between napping and cardiometabolic traits.

Nature Communications · Feb 10, 2021Peer-reviewedGenetic & Genomic Medicine

Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

Kristi Krebs, Jonas Bovijn, Neil S. Zheng, Maarja Lepamets, Jenny C. Censin, Tuuli Jürgenson, Dage Särg, Erik Abner, Triin Laisk, Yang Luo, Line Skotte, Frank Geller, Bjarke Feenstra, Wei Wang, Adam Auton, , João Fadista

The paper identifies HLA-B*55:01 as a genetic risk factor for penicillin allergy through genome-wide analysis of electronic health records and imputed HLA data.

The American Journal of Human Genetics · Sep 3, 2020Peer-reviewedGenetics