Author

Nadia Alawar

Saarland UniversityORCID 0000-0002-8591-2513Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Hsin‐Fang ChangiD· 3 shared Ute BechereriD· 3 shared Abed Alrahman ChouaibiD· 2 shared Claudia SchirraiD· 2 shared Szu-Min TuiD· 2 shared Ali H. ShaibiD· 1 shared Anna OnnisiD· 1 shared Annachiara Miccoli· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

Hsin‐Fang ChangORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Highly adaptable deep-learning platform for automated detection and analysis of vesicle exocytosis

Abed Alrahman Chouaib, Hsin‐Fang Chang, Omnia M. Khamis, Nadia Alawar, Santiago Echeverry, Lucie Demeersseman, Sofia Elizarova, James A. Daniel, Xiao Yu Tian, Peter Lipp, Eugenio F. Fornasiero, Salvatore Valitutti, Sebastian Barg, Constantin Pape, Ali H. Shaib, Ute Becherer

The paper introduces IVEA, a deep-learning platform for automated exocytosis analysis in live-cell imaging, which is faster and more reliable than manual methods.

Nature Communications · Jul 12, 2025Peer-reviewedBioengineering

Thrombospondins 1 and 4 undergo coordinated transport to multicore cytotoxic granules to regulate SMAP biogenesis and function in CTL-mediatedcytotoxicity

Chiara Cassioli, Nagaja Capitani, Claire C. Staton, Claudia Schirra, Francesca Finetti, Anna Onnis, Nadia Alawar, Szu-Min Tu, Ludovica Lopresti, Vanessa Tatangelo, Carmela Tangredi, Salvatore Valvo, Hsin‐Fang Chang, Annachiara Miccoli, Ewoud Bernardus Compeer, , Cosima T. Baldari

This study shows TSP-4 is required for TSP-1 association with lytic granules and SMAP-mediated cytotoxicity in CTLs, and its expression is suppressed in CLL cell supernatants.

Proceedings of the National Academy of Sciences · Feb 4, 2025Peer-reviewedImmunology

Lytic IFNγ is stored in granzyme B-containing cytotoxic granules and co-secreted by effector CD8⁺ T cells

Xuemei Li, Claudia Schirra, Marie-Louise Wirkner, Szu-Min Tu, Chin-Hsin Lin, Meltem Hohmann, Nadia Alawar, Abed Alrahman Chouaib, Ute Becherer, Varsha Pattu, Jens Rettig, Elmar Krause, Hsin‐Fang Chang

The paper identifies lytic IFNγ stored in granzyme B-containing cytotoxic granules and co-secreted with GzmB by effector CD8⁺ T cells during immunological synapse formation.

bioRxiv · Jan 29, 2025 · PreprintImmunology