Author

Ufuk Günesdogan

University of GöttingenORCID 0000-0002-8658-8022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Fereshteh TorabiiD· 3 shared Oleksandr DovgushaiD· 3 shared Stefan SchoenfelderiD· 3 shared Julia Kurlovich· 2 shared Stephen Bevan· 2 shared Alice SantambrogioiD· 1 shared Ander Movilla MiangolarraiD· 1 shared Ayyub EbrahımıiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersSystems Biology

Fereshteh TorabiORCID

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4 papers

Recent·Most cited

Signatures of digital Polycomb regulation in functional iPSC heterogeneity between individuals

Ander Movilla Miangolarra, Julia Kurlovich, Fereshteh Torabi, Oleksandr Dovgusha, Yang Cao, Lihan Lin, Ufuk Günesdogan, Stefan Schoenfelder, Martin Howard

The paper identifies Polycomb-regulated gene expression and chromatin state differences in iPSCs that correlate with differentiation efficiency.

bioRxiv · Jul 25, 2025 · PreprintSystems Biology

Non-canonical enhancers control gene expression and cell fate in human pluripotent stem cells

Yang Cao, Oleksandr Dovgusha, Ayyub Ebrahımı, Stephen Bevan, Lukas Widmer, Fereshteh Torabi, Julia Kurlovich, Ignacio Rodríguez-Polo, Soumen Khan, Manthan Patel, Madapura M. Pradeepa, Ufuk Günesdogan, Stefan Schoenfelder

The paper identifies non-canonical enhancers in human pluripotent stem cells that lack typical enhancer features but regulate gene expression and cell fate.

bioRxiv · Jun 1, 2025 · PreprintGenomics

Epigenetic priming of embryonic enhancer elements coordinates developmental gene networks

Christopher D Todd, Jannat Ijaz, Fereshteh Torabi, Oleksandr Dovgusha, Stephen Bevan, Olivia Cracknell, Tim Lohoff, Stephen Clark, Ricard Argelaguet, Juliette Pearce, Ioannis Kafetzopoulos, Alice Santambrogio, Jennifer Nichols, Ferdinand von Meyenn, Ufuk Günesdogan, , Wolf Reik

The paper identifies epigenetically primed enhancers in early embryonic development and shows their role in regulating developmental gene networks across species.

bioRxiv · Sep 9, 2024 · PreprintDevelopmental Biology

Tracing the Transitions from Pluripotency to Germ Cell Fate with CRISPR Screening

Jamie A. Hackett, Yun Huang, Ufuk Günesdogan, Kristjan H. Gretarsson, Toshihiro Kobayashi, M. Azim Surani

This study identifies key regulators of the transition from pluripotency to germ cell fate using CRISPR screening in PGC-like cells, highlighting Nr5a2 and Zfp296 as critical factors.

Nature Communications · Oct 10, 2018Peer-reviewedDevelopmental Biology