Author

Pascal Benz

Universitätsklinikum TübingenORCID 0000-0002-8737-9441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

Aistė Skorupskaitė· 1 shared Alexander VisekrunaiD· 1 shared Christoph K. Stein‐ThoeringeriD· 1 shared Dirk Hans BuschiD· 1 shared Fabian FreitagiD· 1 shared Fabian Nikolka· 1 shared Felipe PrósperiD· 1 shared G. BrevesiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Aistė Skorupskaitė

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2 papers

Recent·Most cited

Development and Characterization of a 2D Porcine Colonic Organoid Model for Studying Intestinal Physiology and Barrier Function

Masina Plenge, Nadine Schnepel, Mathias Müsken, Judith Rohde, Ralph Goethe, G. Breves, Gemma Mazzuoli‐Weber, Pascal Benz

This paper develops and characterizes a 2D porcine colonic organoid model that mimics native colon tissue for studying intestinal physiology and barrier function.

PLoS ONE · May 7, 2025Peer-reviewedPhysiology

Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells

Sarah Staudt, Fabian Nikolka, Markus Perl, Julia Franz, Noémie Leblay, Xiaoli-Kat Yuan, M. Larrayoz, Teresa Lozano, Linda Warmuth, Matthias A. Fante, Aistė Skorupskaitė, Teng Fei, Maria Bromberg, Patxi San Martín‐Úriz, Juan R. Rodríguez-Madoz, , Maik Luu

This study shows that pentanoate, a microbial postbiotic, is metabolized to citrate, which influences T cell differentiation and anti-cancer CAR T cell efficacy through epigenetic mechanisms.

bioRxiv · Aug 19, 2024 · PreprintImmunology