Helen Farrants

The paper introduces a machine learning-enabled pipeline for volumetric FLIM imaging in living systems, enabling long-term and high-speed data acquisition and analysis.

WHaloForce is a chemigenetic tension sensor that images molecular forces in living cells and animals, revealing tissue-specific force patterns and ovulation-related molecular loading.

This study shows that reducing Letm1 increases mitochondrial Ca2+ retention, overactivates metabolism, and enhances long-term memory in flies and mice.

This paper introduces new organellar Ca2+ sensors with tunable colors and improved brightness and photostability for multiplexed measurements in different organelles.

The paper introduces WHaloCaMP, a near-infrared calcium indicator, and demonstrates its use in imaging calcium responses in various organisms.

This paper describes an engineered nanobody that modulates GFP binding with small molecules, enabling controlled study of GFP fusion proteins in biological processes.