Cancer BiologyHepatologyPeer-reviewed
Hepatocyte MLKL Drives Obesity-Driven Hepatocellular Carcinoma Progression via Mitochondrial Dysfunction Independent of Necroptosis in MASLD
Phoebe Ohene-Marfo, Sabira Mohammed, Chao Jiang…·Sathyaseelan S. Deepa
This study shows that hepatocyte MLKL promotes obesity-driven MASLD-HCC through mitochondrial dysfunction and MFN2 suppression, independent of necroptosis.
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