Author

Mariela Faykoo-Martinez

University of TorontoORCID 0000-0002-8885-657XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

Dustin SokolowskiiD· 5 shared Huayun HouiD· 5 shared Michael D. WilsoniD· 5 shared Cadia ChaniD· 4 shared Anna GoldenbergiD· 3 shared Melissa M. HolmesiD· 3 shared Alexander NateriD· 2 shared Anna R. Roy· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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5 shared papersGenomics

Dustin SokolowskiORCID

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5 papers

Recent·Most cited

Decoding the naked mole-rat genome, telomere to telomere

Dustin Sokolowski, Alexander Nater, Mihai Miclăuș, Wenjian Meng, Simon Monis, Wing Yui Ngan, Runjia Qu, Jason Erdmann, Alyssa M. Fontanilla, Vladimir A. Trifonov, DongAhn Yoo, Sana Akhtar Alvi, Alison J. Barker, Odei Barreñada, Jonathan Bayerl, , Gabriel Balmus

The paper presents a telomere-to-telomere genome assembly of the naked mole-rat and compares it with a related species to identify gene losses and duplications associated with unique traits.

bioRxiv · Oct 16, 2026 · PreprintGenomics

An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology

Dustin Sokolowski, Mihai Miclăuș, Alexander Nater, Mariela Faykoo-Martinez, Kendra Hoekzema, Philip C. Zuzarte, Simon Monis, Sana Akhtar Alvi, Jason Erdmann, Archana Lal Erdmann, Kumaragurubaran Rathnakumar, Jonathan Bayerl, DongAhn Yoo, Nadia Karimpour, Kyra Ungerleider, , Michael D. Wilson

The paper presents an updated reference genome for the naked mole-rat, identifying gene losses and gains linked to its unique physiological traits.

bioRxiv · Nov 26, 2024 · PreprintGenomics

Age, sex, and cell type-resolved hypothalamic gene expression across the pubertal transition in mice

Dustin Sokolowski, Huayun Hou, Kyoko E. Yuki, Anna R. Roy, Cadia Chan, Wendy W. Y. Choi, Mariela Faykoo-Martinez, Matt Hudson, Christina Corre, Liis Uusküla-Reimand, Anna Goldenberg, Mark R. Palmert, Michael D. Wilson

The paper analyzes hypothalamic gene expression in mice across puberty, identifying age- and sex-specific changes and their association with pubertal regulation.

Biology of Sex Differences · Oct 24, 2024Peer-reviewedGenomics

Postnatal developmental trajectory of sex-biased gene expression in the mouse pituitary gland

Huayun Hou, Cadia Chan, Kyoko E. Yuki, Dustin Sokolowski, Anna R. Roy, Rihao Qu, Liis Uusküla-Reimand, Mariela Faykoo-Martinez, Matt Hudson, Christina Corre, Anna Goldenberg, Zhaolei Zhang, Mark R. Palmert, Michael D. Wilson

This study profiles gene and miRNA expression in mouse pituitaries across postnatal ages to identify sex-biased gene regulation and cell-type proportion differences during development.

bioRxiv · Jan 5, 2022 · PreprintGenomics

Single-cell mapper (scMappR): using scRNA-seq to infer cell-type specificities of differentially expressed genes

Dustin Sokolowski, Mariela Faykoo-Martinez, Lauren Erdman, Huayun Hou, Cadia Chan, Helen Zhu, Melissa M. Holmes, Anna Goldenberg, Michael D. Wilson

scMappR assigns cell-type specificity scores to bulk RNA-seq DEGs using scRNA-seq data and deconvolution methods, showing accurate assignment in kidney regeneration analysis.

NAR Genomics and Bioinformatics · Jan 6, 2021Peer-reviewedBioinformatics