Jong‐Seo Kim

Spatial Metabolomics by Desthiobiotin Ligase (DESTNI) in Live Cells

This paper introduces DESTNI, a proximity labeling tool for spatial metabolomics, and demonstrates its application in identifying compartment-specific amino metabolite signatures in live cells.

MitoAtlas: a Domain-Resolved Spatial Map of the HumanMitochondrial Proteome

MitoAtlas maps the sub-mitochondrial localization and topology of 861 proteins using SR-PL and AlphaFold, identifying new interactions and unannotated proteins.

Structural basis of the catalytic and allosteric mechanism of bacterial acetyltransferase PatZ

This paper determines the structure of Escherichia coli PatZ, revealing its homotetrameric architecture and the role of the regulatory domain in catalytic activity and substrate specificity.

Serpina1e mediates the exercise-induced enhancement of hippocampal memory

This study identifies Serpina1e as a myokine that enhances hippocampal memory through neurotrophic signaling, showing its migration from blood to brain and effects on neurogenesis and BDNF.

Cellular dsRNA interactome reveals the regulatory map of exogenous RNA sensing

The paper identifies cellular dsRNA-binding proteins (dsRBPs) using anti-dsRNA immunoprecipitation and mass spectrometry, revealing their role in regulating the interferon response and antiviral defense against HCoV-OC43.

ERH as a component of the Microprocessor facilitates the maturation of suboptimal microRNAs

This study identifies ERH as a new component of the Microprocessor complex that enhances processing of suboptimal pri-miRNAs in polycistronic clusters.