Masamichi Yamamoto

Visualization of intracellular ATP dynamics in the whole kidney under pathophysiological conditions using the kidney slice culture system

The paper establishes a novel ATP imaging system using kidney slice cultures to study intracellular ATP dynamics under pathophysiological conditions and evaluates ATP synthesis pathways in different kidney cell types.

Lysine demethylase 7a regulates the anterior-posterior development in mouse by modulating the transcription of Hox gene cluster

This study shows that Kdm7a regulates posterior Hox gene expression in mouse embryos by demethylating H3K9me2, leading to anterior-posterior developmental defects.

Microglia-triggered hyperexcitability in the cerebellum depresses animal behaviors

The paper shows that microglia activation in the cerebellum increases neuronal excitability and leads to behavioral impairments, which can be reversed by inhibiting microglia or TNF-.