Author

Mónica L. Guzmán

Weill Cornell MedicineORCID 0000-0002-9262-8246Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Gail J. RoboziD· 2 shared Joshua Alexander FeiniD· 2 shared Leandro Marcelo MartineziD· 2 shared Aksharh Thambipillai· 1 shared Aleksandra KopacziD· 1 shared Alyssa D. RetiziD· 1 shared Amy ChadburniD· 1 shared Arvin Ruiz· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

Gail J. RobozORCID

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Author profile →

3 papers

Recent·Most cited

eIF4E and Ezrin cooperate in pseudopods to drive a localized migratory translation program in acute myeloid leukemia

Biljana Čuljković, Leandro Marcelo Martinez, Naiyu Shi, Alyssa D. Retiz, Samuel Perron, Aksharh Thambipillai, Caleb M. Embree, Winnie Yip, Vicenta Trujillo-Alonso, Emma Lassman, Marysol Chu Carty, Kata Alilovic, Sébastien Carreno, Gail J. Roboz, Mónica L. Guzmán, Katherine L. B. Borden

In acute myeloid leukemia, Ezrin binds eIF4E and anchors active ribosomes in pseudopods for local translation of CD44 and hyaluronan pathway proteins; eIF4E loss impairs mouse engraftment.

bioRxiv · Oct 2, 2026 · PreprintCancer Biology✦ In-depth digest

Spatial remodeling of bone marrow architecture defines tissue-state signatures of disease activity and therapeutic response in myelodysplastic neoplasms

Ryan Nachman, Aleksandra Kopacz, Caitlin Unkenholz, Jian Chai, Arvin Ruiz, Itzel Valencia, Jeanne Jiang, Fabio Socciarelli, Jiwoon Park, Christopher E. Mason, Ling Zhang, David Andrew Sallman, Gail J. Roboz, Pinkal M. Desai, Justin Kaner, , Sanjay S. Patel

This study uses spatial imaging to identify architectural changes in bone marrow that predict disease activity and response to therapy in myelodysplastic neoplasms.

Leukemia · Jun 30, 2026Peer-reviewedPathology

Total body irradiation primes CD19-directed CAR T cells against large B-cell lymphoma

Mohammad Alhomoud, Michelle Foley, Mayumi Sugita, Joshua Alexander Fein, Samuel Yamshon, Leandro Marcelo Martinez, Kai Rejeski, Maider Astorkia, Doron Betel, Renier J. Brentjens, Koen van Besien, Lorenzo Galluzzi, Olivier Boyer, J. Martinet, Silvia Chiara Formenti, Mónica L. Guzmán

This study shows that total body irradiation before CAR T cell infusion enhances their effectiveness against large B-cell lymphoma by improving cytotoxicity and survival outcomes.

bioRxiv · Mar 17, 2025 · PreprintCancer Biology