Ancient co-option of LTR retrotransposons as yeast centromeres
Max A. B. Haase, Luciana Lazar‐Stefanita, Lyam Baudry, Aleksandra M. Wudzinska, Xiaofan Zhou, Antonis Rokas, Chris Todd Hittinger, Boris Pfander, Andrea Musacchio, Jef D. Boeke
The paper identifies proto-point centromeres in Saccharomycodales yeast, showing they evolved from retrotransposon LTRs, supporting the hypothesis that point centromeres originated from ancestral retrotransposons.
Nature · Feb 18, 2026Peer-reviewedEvolutionary Biology