Vittore F. Scolari

This paper uses Hi-C data to infer 3D genome structure and chromatin dynamics in budding yeast without prior assumptions about nuclear organization.

The paper identifies Esc1-mediated telomere anchoring as a mechanism regulating telomere clustering in yeast during metabolic shifts to quiescence.

The paper develops a theory to predict how molecular crowding affects the extension of stretched DNA under tension, showing both compression and expansion effects depending on crowder density and size.

The paper uses optogenetic tools to control pheromone gradients in budding yeast, enabling spatial regulation of mating behavior and cell fusion.

This paper uses optogenetics to control cooperation and cheating in yeast populations, showing that cooperation is most effective when cooperator domain size is constrained between two length-scales.

The paper shows that dense Rap1 arrays block DNA loop extrusion by condensin in yeast, acting as contact insulators and affecting dicentric chromosome resolution.

Chromosight detects patterns in Hi-C contact maps with greater sensitivity and speed than existing methods, applicable to various genomes.

The paper redesigns a genomic region for improved Hi-C analysis, revealing insights into homolog pairing and loop formation during meiosis.

The paper uses Hi-C to analyze chromosome structure dynamics in budding yeast during the cell cycle, revealing SMC-dependent structural transitions and mitotic reorganization.