Chemically encoded pH-tunable covalent adhesion by a bacterial thioester domain
Yuki Tokunaga, Ryo Matsunaga, Hiroko Kozuka‐Hata, Masaaki Oyama, Kouhei Tsumoto
This study shows that thioester domains in bacterial adhesins enable pH-responsive covalent adhesion, with reversible binding regulated by pH changes.
bioRxiv · Apr 3, 2026 · PreprintBiochemistry