Author

Amro A. Hussien

University of ZurichORCID 0000-0002-9324-9360Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Jess Gerrit SnedekeriD· 2 shared Archana G. MohananiD· 1 shared Barbara P. Niederöst· 1 shared Bart GhesquièreiD· 1 shared Courtney M. KarneriD· 1 shared Diane E. TayloriD· 1 shared Didier SurdeziD· 1 shared Dirk Sw ElewautiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Jess Gerrit SnedekerORCID

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2 papers

Recent·Most cited

Cell BiologyScience Translational MedicinePeer-reviewedJan 7, 2026

✦ In-depth digest

HIF1α gates tendon response to overload and drives tendinopathy independently of vascular recruitment

Greta Moschini, Archana G. Mohanan, Izabella S. Niewczas…·Jess Gerrit Snedeker

Mechanical overload activates hypoxia-inducible factor 1-alpha (HIF1a) in tenocytes to drive tendinopathy independently of VEGFA-mediated vascular ingrowth, and tenocyte Hif1a deletion prevents overload-induced tendon degeneration in mice.

12 citationstop 1%

humanmouse

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Developmental BiologyeLifePeer-reviewedJul 28, 2021

A G protein-coupled receptor is required in cartilaginous and dense connective tissues to maintain spine alignment

Zhaoyang Liu, Amro A. Hussien, Yunjia Wang…·Ryan S. Gray

This study identifies Adgrg6 as essential for maintaining spine alignment by regulating biomechanical properties and gene expression in connective tissues, offering therapeutic insights for adolescent idiopathic scoliosis.

31 citationstop 4%

mouseexperimental assay

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