Author

Anne Jacobi

Boston Children's HospitalORCID 0000-0002-8197-3554Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Joshua R. SanesiD· 4 shared Wenjun YaniD· 3 shared Zhigang HeiD· 3 shared Feng TianiD· 2 shared Inbal BenhariD· 2 shared Karthik ShekhariD· 2 shared Nicholas M. TraniD· 2 shared Aboozar MonavarfeshaniiD· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersNeuroscience

Joshua R. SanesORCID

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4 papers

Recent·Most cited

Core Transcription Programs Controlling Injury-Induced Neurodegeneration of Retinal Ganglion Cells

Feng Tian, Yuyan Cheng, Songlin Zhou, Qianbin Wang, Aboozar Monavarfeshani, Kun Gao, Weiqian Jiang, Riki Kawaguchi, Qing Wang, Mingjun Tang, Ryan Donahue, Huyan Meng, Yu Zhang, Anne Jacobi, Wenjun Yan, , Zhigang He

The paper identifies four ATF/CEBP transcription factors that drive injury-induced neurodegeneration of retinal ganglion cells and shows their role in glaucoma.

Neuron · Jun 28, 2022Peer-reviewedNeuroscience

Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells

Anne Jacobi, Nicholas M. Tran, Wenjun Yan, Inbal Benhar, Feng Tian, Rebecca Schaffer, Zhigang He, Joshua R. Sanes

The paper identifies transcriptional programs that enhance survival and axon regeneration of injured retinal ganglion cells using single-cell transcriptomics and computational analysis.

Neuron · Jun 28, 2022Peer-reviewedNeuroscience

Unified classification of mouse retinal ganglion cells using function, morphology, and gene expression

Jillian J. Goetz, Zachary F. Jessen, Anne Jacobi, Adam Mani, Sam Cooler, Devon Greer, Sabah Kadri, Jeremy P. Segal, Karthik Shekhar, Joshua R. Sanes, Gregory W. Schwartz

The paper classifies mouse retinal ganglion cells into 42 types using functional, morphological, and transcriptomic data and provides an online database for classification.

Cell Reports · Jan 1, 2021Peer-reviewedNeuroscience

Single-cell profiles of retinal neurons differing in resilience to injury reveal neuroprotective genes

Nicholas M. Tran, Karthik Shekhar, Irene E. Whitney, Anne Jacobi, Inbal Benhar, Guosong Hong, Wenjun Yan, Xian Adiconis, McKinzie E. Arnold, Jung Min Lee, Joshua Z. Levin, Dingchang Lin, Chen Wang, Charles M. Lieber, Aviv Regev, , Joshua R. Sanes

The paper identifies neuroprotective genes in retinal ganglion cells by analyzing their resilience to injury using single-cell RNA-seq and functional assays.

Neuron · Nov 26, 2019Peer-reviewedNeuroscience