Janell L.M. Smith

The Energetic Cost of Adrenergic Signaling in Primary Human Fibroblasts

This study quantifies the energetic cost of norepinephrine signaling in primary human fibroblasts, revealing dynamic changes in glycolysis and oxidative phosphorylation over time.

Mapping the GDF15 Arm of the Integrated Stress Response in Human Cells and Tissues

The paper develops an ISRGDF15 index to quantify the GDF15 arm of the ISR in human cells and tissues, showing its upregulation in specific tissues and correlation with age.

Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues

This study combines Ngn2 overexpression with small molecule patterning to efficiently generate lower induced Motor Neurons (liMoNes) from hPSCs, achieving high yields and functional characteristics.