Author

Rosa Barrio

CIC bioGUNEORCID 0000-0002-9663-0669Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:proteomics· 1

Frequent Co-Authors

Félix ElortzaiD· 2 shared Ibón IloroiD· 2 shared James David SutherlandiD· 2 shared Mikel AzkargortaiD· 2 shared Ainara Miranda Villanueva· 1 shared Ainhoa Urcullu· 1 shared Álvaro Serrano‐MorrásiD· 1 shared Amaia Zabala‐LetonaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersCancer Biology

Félix ElortzaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of UFMylation supports prostate cancer metastasis and rewires cell metabolism towards hexosamine biosynthesis

Laura Bozal‐Basterra, María-Camila Salazar, Ana Margarida Ferreira Campos, Margherita Demicco, Daniel R. Schmidt, Klaudia Sobczak, June Ereño‐Orbea, Patricia Altea‐Manzano, Ainara Miranda Villanueva, Belen Martinez-Laosa, Saioa Garcia‐Longarte, María Ponce-Rodriguez, Isabel Mendizabal, Onintza Carlevaris, Ianire Astobiza, , Arkaitz Carracedo

This study shows that loss of UFMylation promotes prostate cancer metastasis by reprogramming glucose metabolism towards hexosamine biosynthesis.

bioRxiv · Jun 2, 2025 · PreprintCancer Biology

Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome

Laura Merino‐Cacho, Orhi Barroso‐Gomila, Mónica Pozo-Rodríguez, Veronica Muratore, Claudia Guinea-Pérez, Álvaro Serrano‐Morrás, Coralia Pérez, Sandra Cano-López, Ainhoa Urcullu, Mikel Azkargorta, Ibón Iloro, Carles Galdeano, Jordi Juárez‐Jiménez, Ugo Mayor, Félix Elortza, , James David Sutherland

The paper demonstrates that BioE3 can identify endogenous substrates and neosubstrates of Cullin-RING ligases, revealing changes in the ubiquitination landscape upon molecular glue treatment.

Cell Communication and Signaling · Feb 19, 2025Peer-reviewedCell Biology

Synaptogyrin regulates neuronal activity dependent autophagy to degrade synaptic vesicle components and pathological Tau

Sergio Hernández-Díaz, Pilar Martinez-Olondo, Irene Sanchez-Mirasierra, Carla Montecinos-Oliva, Saurav Ghimire, James D. Sutherland, Rosa Barrio, Sandra‐Fausia Soukup

This study identifies Synaptogyrin as a negative regulator of activity-dependent synaptic autophagy, showing its role in degrading synaptic vesicle components and pathological Tau.

bioRxiv · Jul 4, 2023 · PreprintNeuroscience