Author

Madeleine R. Sorensen

University of Colorado AnschutzORCID 0000-0002-9747-4178Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam M. DrobishiD· 1 shared Alexander TropshaiD· 1 shared Che-Kang ChangiD· 1 shared Craig E. CameroniD· 1 shared Devdoot S. MajumdariD· 1 shared Dr Paul Sylvester· 1 shared Ian T. BaileyiD· 1 shared Jacob DearborniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMicrobiology

Adam M. DrobishORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Proximity proteomics reveals a role for IFI16 during human coronavirus infection

Sylvester Languon, Ian T. Bailey, Madeleine Sorensen, Zachary D. Miller, Jihui Sha, Jacob Dearborn, William Dowell, Tylar Kirch, James Wohlschlegel, Devdoot S. Majumdar

The paper identifies IFI16 as a host protein interacting with SARS-CoV-2 NSP8/NSP10, showing that IFI16 promotes coronavirus infection independently of its role in type I IFN regulation.

bioRxiv · Apr 23, 2026 · PreprintMicrobiology

Novel Computational Pipeline to Identify Target Sites for Broad Spectrum Antiviral Drugs

John D. Sears, Konstantin Popov, Dr Paul Sylvester, Rebekah J. Dickmander, Jennifer Loome-Diaz, Che-Kang Chang, Julia Huff, Wes Sanders, Noore Saba, Madeleine R. Sorensen, Adam M. Drobish, Nicholas A. May, Kevin E. W. Namitz, Julia Ann Fecko, Jamie J. Arnold, , Nathaniel J. Moorman

This paper develops a computational pipeline to identify conserved antiviral target sites in alphaviruses using AI-driven methods, validating potential drug targets through mutagenesis.

Antiviral Research · Dec 1, 2025Peer-reviewedMicrobiology