Anubhav Prakash

SOX2-dependent enhancer activation couples epithelial identity to neuronal maintenance

This study shows that SOX2 maintains regulatory continuity between cochlear epithelium and spiral ganglion neurons by sustaining enhancer activity and neurotrophic gene expression.

Tissue-scale mechanics controls differentiation strategy and dynamics of epithelial multilayering

The paper shows that tissue mechanics control epithelial multilayering by regulating cell differentiation and movement strategies in the developing mouse epidermis.

Coexistence of asymmetric cell shape dynamics governs organisational diversity in sensory epithelia

The paper identifies cell-shape dynamics as a mechanism for generating organisational diversity in sensory epithelia across species.

Role Of Pcdh15 In The Development Of Intrinsic Polarity Of Inner Ear Hair Cells

The paper investigates the role of Pcdh15-CD2 in establishing intrinsic polarity of inner ear hair cells, showing its necessity for kinocilial migration and polarity restoration.

Force patterning drives cell flows and 3D spatial order in auditory epithelia

The paper shows that patterned junctional contractility coordinates cell behavior in mixed epithelia, leading to spatial order and 3D tissue structure during development.

Compartment coupling integrates patterning and morphogenetic information during development

The paper investigates how compartment coupling coordinates patterning and morphogenetic information in the mouse organ of Corti, revealing vinculin-dependent junctional mechanics as a key mechanism.