Author

Alexander Ernst

University of BernORCID 0000-0002-9979-8002Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:zebrafish· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Nadia MercaderiD· 3 shared Héctor Sánchez-IranzoiD· 2 shared Juan Manuel González‐RosaiD· 2 shared María Galardi‐CastillaiD· 2 shared Agnese KocereiD· 1 shared Alexa BurgeriD· 1 shared Andrés Sanz-MorejóniD· 1 shared Anthony B. FirulliiD· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersDevelopmental Biology

Nadia MercaderORCID

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3 papers

Recent·Most cited

Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma

Karin D. Prummel, Helena Lucia Crowell, Susan Nieuwenhuize, Eline Constance Brombacher, Stephan Daetwyler, Charlotte Soneson, Jelena Kresoja‐Rakic, Agnese Kocere, Manuel Ronner, Alexander Ernst, Zahra Labbaf, David E. Clouthier, Anthony B. Firulli, Héctor Sánchez-Iranzo, Sundar R Naganathan, , Christian Mosimann

This study identifies Hand2 as a key regulator of mesothelium progenitors in zebrafish and shows its reactivation in mesothelioma, linking developmental processes to disease.

bioRxiv · Nov 11, 2020Developmental Biology

Actomyosin dynamics, Bmp and Notch signaling pathways drive apical extrusion of proepicardial cells

Laura Andrés‐Delgado, Alexander Ernst, María Galardi‐Castilla, David Bazaga, Marina Peralta, Juliane Münch, Juan Manuel González‐Rosa, Federico Tessadori, Jeroen Bakkers, José Luís de la Pompa, Julien Vermot, Nadia Mercader

The paper identifies actomyosin dynamics and Notch/Bmp signaling as drivers of apical extrusion of proepicardial cells in zebrafish during heart development.

bioRxiv · Jun 5, 2018 · PreprintDevelopmental Biology

Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart

Héctor Sánchez-Iranzo, María Galardi‐Castilla, Andrés Sanz-Morejón, Juan Manuel González‐Rosa, Ricardo Costa, Alexander Ernst, Julio Sainz de Aja, Xavier Langa, Nadia Mercader

The paper investigates fibrosis resolution in regenerating zebrafish hearts, finding that fibroblasts become inactivated rather than being eliminated, and that fibrosis supports cardiomyocyte proliferation.

Proceedings of the National Academy of Sciences · Apr 2, 2018Peer-reviewedDevelopmental Biology