Author

Mareike Schell

Boston Children's HospitalORCID 0000-0002-9999-445XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

George Pengo· 1 shared Ivana SemovaiD· 1 shared Joanna KrawczykiD· 1 shared Kiran J. Biddinger· 1 shared Krishna G. AragamiD· 1 shared Linus T.-Y. TsaiiD· 1 shared Marcia C. HaigisiD· 1 shared Matt KankeiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

George Pengo

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1 paper

Recent·Most cited

The Diabetes Gene Tcf7l2 Organizes Gene Expression in the Liver and Regulates Amino Acid Metabolism

Joanna Krawczyk, William O’Connor, Pedro Henrique Vendramini, Mareike Schell, Kiran J. Biddinger, Matt Kanke, George Pengo, Ivana Semova, Tiffany Fougeray, Marcia C. Haigis, Krishna G. Aragam, Wouter H. Lamers, Linus T.-Y. Tsai, Praveen Sethupathy, Sudha B. Biddinger

This study shows Tcf7l2 maintains hepatic zonation and glutamine homeostasis, with loss of Tcf7l2 causing metabolic disruption and decreased glutamine levels.

Molecular Metabolism · Jul 16, 2025Peer-reviewedPhysiology