Author

Ruizhen Li

Ottawa Hospital Research InstituteORCID 0000-0003-0092-4580Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ruizhen Li1 paper · The University of Texas at San Antonio Health Science Center

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

X. Johné LiuiD· 3 shared Florance Parweez· 2 shared Mike TyersiD· 2 shared Roger PalouiD· 2 shared Almer M. van der SlootiD· 1 shared Brian K. CoombesiD· 1 shared D. William CameroniD· 1 shared Damian M. CarragheriD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersSynthetic Biology

X. Johné LiuORCID

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3 papers

Recent·Most cited

Synthetic BiologyFrontiers in NeurosciencePeer-reviewedOct 31, 2025

Engineered spermidine-secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster

Florance Parweez, Roger Palou, Ruizhen Li…·X. Johné Liu

Engineered spermidine-secreting Saccharomyces boulardii improves olfactory memory in Drosophila without affecting locomotion.

1 citation

Drosophilaexperimental assay

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Cancer BiologyScientific ReportsPeer-reviewedAug 30, 2025

Engineered spermidine-secreting Saccharomyces boulardii ameliorate colitis and colon cancer in mice

Mahdi Mohaqiq, Roger Palou, Ruizhen Li…·X. Johné Liu

This study engineers S. boulardii to secrete spermidine, showing improved efficacy in reducing colitis and colon cancer in mice compared to wild-type strains.

5 citations

mousegenetic perturbation / CRISPR

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Cell BiologybioRxivPreprintAug 30, 2018

Calcium nanodomains in spindles

Guolong Mo, Ruizhen Li, Zachary Swider…·X. Johné Liu

This study identifies calcium nanodomains associated with spindles in Xenopus eggs, embryos, and HeLa cells, showing their essential role in spindle assembly and stability.

DOI 10.1101/404715

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