Yetiş Gültekin

This study shows that physiological folate levels limit nucleotide synthesis in leukemia cells, making them reliant on salvage pathways for proliferation.

This study shows pancreatic cancer disrupts normal pancreatic function, leading to systemic nutrient depletion and muscle wasting, with autophagy in muscle playing a key role in nutrient redistribution to support tumor growth.

This study shows that single nutrients do not determine breast cancer metastasis sites, and identifies purine synthesis as a key factor across multiple tissues.

This study examines how aging affects glucose and lipid metabolism in mice, finding that NAD+ levels remain stable but lipid metabolism increases in aged tissues.

This study shows that Iduna regulates Axin proteolysis, which controls stem cell proliferation and intestinal homeostasis in Drosophila.