Author

Sydney K. Hart

New York Genome CenterORCID 0000-0003-0228-6471Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Alejandro Méndez‐MancillaiD· 1 shared Anastasiia OnyshchenkoiD· 1 shared Ariella L. G. Coler-ReillyiD· 1 shared Damon T. BurrowiD· 1 shared Gediminas DrabaviciusiD· 1 shared Hans‐Hermann WesselsiD· 1 shared India C. Bradley· 1 shared Jan E. CaretteiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Alejandro Méndez‐MancillaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GenomicsNature BiotechnologyPeer-reviewedFeb 11, 2025

Low copy CRISPR-Cas13d mitigates collateral RNA cleavage

Sydney K. Hart, Simon Müller, Hans‐Hermann Wessels…·Neville E. Sanjana

The paper evaluates collateral RNA cleavage in CRISPR-Cas13d systems and finds that low-copy expression reduces off-target effects while maintaining on-target knockdown.

35 citationstop 1%

humanCRISPR screen

𝕏 PostBluesky

GenomicsbioRxivPreprintApr 10, 2020

Sphingolipid Biosynthesis Inhibition As A Host Strategy Against Diverse Pathogens

Sandeep Kumar, Jinmei Li, Jiwoong Park…·Timothy R. Peterson

This study identifies that multiple cationic amphipathic drugs (CADs) share molecular similarities with chloroquine and inhibit sphingolipid biosynthesis, suggesting their potential as antiviral agents against diverse pathogens including SARS-CoV-2.

3 citations

humanstatistical model

𝕏 PostBluesky