Author

Michael G. Thomas

University of DundeeORCID 0000-0003-0377-0281Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Michèle Francoeur· 1 shared Alysia Bryant· 1 shared Carson Semple· 1 shared César Mendoza-MartíneziD· 1 shared Chou-Wei ChangiD· 1 shared Chris ChatzinakosiD· 1 shared David HorniD· 1 shared Jagmohan Saini· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

A. Michèle Francoeur

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedFeb 4, 2026

Decoding efficacy and resistance space at a drug binding site

Simone Altmann, César Mendoza-Martínez, Melanie C. Ridgway…·David Horn

The paper uses MOT-library profiling to assess all possible mutations at a drug binding site and predicts resistance mechanisms through computational modeling.

1 citation

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioengineeringbioRxivPreprintSep 24, 2024

Engineering Human ARMMs as Therapeutic Non-Viral Vehicles for in vivo Delivery of Genome Editing Payloads

Qiyu Wang, Shu-Lin Liu, Wen‐Ning Zhao…·Joseph F. Nabhan

This paper engineers human-derived ARMMs for in vivo delivery of genome editing tools, showing efficient gene knockout and therapeutic potential in mouse models.

DOI 10.1101/2024.09.24.614725

mousehuman

𝕏 PostBluesky