Joshua Tran

The paper shows that ESCRT-III-mediated membrane bending directionality arises from bilayer asymmetry rather than intrinsic ESCRT properties.

This study shows that microtubule lattice conformation and integrity regulate TAT1-mediated α-tubulin acetylation, with expanded lattices enhancing acetylation and compacted lattices reducing it.

This paper introduces MT-DS, a fluorescent probe that directly visualizes microtubule lattice damage, revealing motor-caused damage during motility.

This study identifies an ancient membrane fission mechanism in Asgard archaea, showing ESCRT-III's role in cell compartmentalization predates eukaryogenesis.

This study shows Lgr5+ stem cells maintain intestinal epithelial homeostasis and drive regeneration after injury through WNT signaling.

The paper shows that EB3 comet length at microtubule ends is independent of GTP-cap size, revealing a new mechanism involving phase separation and hydrodynamic instability.